The Best Supplements for PCOS (Polycystic Ovary Syndrome)
PCOS is a complex hormonal condition, and while lifestyle and nutrition are foundational, certain evidence‑based supplements can help manage symptoms, improve hormone balance, and support fertility. Below, I break down the most useful supplements for PCOS — what they do, who they’re for, and how to choose a safe option.
Best Supplements for PCOS
1. Inositol (Myo‑Inositol & D‑Chiro Inositol)
Inositol improves insulin sensitivity, supports ovulation, and may regulate menstrual cycles — key for PCOS management.
Who might benefit most:
Women with irregular cycles
Those trying to conceive
People with signs of insulin resistance
How to choose:
Look for a 40:1 ratio of myo‑inositol to d‑chiro‑inositol
Aim for ~2–4 grams daily, split into 2 doses
Select a third‑party tested powder or capsules
Recommended Brands:
Ovasitol by Theralogix (Inositol Supplement)
2. Multivitamin
Why you need it: PCOS is often associated with nutrient gaps — especially B vitamins, magnesium, zinc, and vitamin D. A high-quality multivitamin helps fill those gaps and support metabolic, hormonal, and reproductive health.
Look for: Third-party tested multis with methylated B vitamins (like B12 and folate), iron if you're menstruating heavily, and without unnecessary fillers.
Recommended Brands:
Pure Encapsulations O.N.E. Multivitamin
3. Vitamin D
Many women with PCOS are deficient in vitamin D, which affects fertility, mood, insulin sensitivity, and inflammation.
Who might benefit most:
Anyone with low blood vitamin D levels
Women with infertility or mood concerns
How to choose:
Opt for D3 (cholecalciferol) form
Combine with K2 if possible for bone health
Check your blood level first if you can
Recommended Brands:
Sports Research Vitamin D3 + K2
4. N‑Acetyl Cysteine (NAC)
NAC is an antioxidant that may improve insulin sensitivity, support egg quality, and reduce oxidative stress in PCOS.
Who might benefit most:
Women trying to conceive
Those with high oxidative stress or poor egg quality
How to choose:
Look for third‑party certified NAC capsules
Common doses range from 600–1800 mg/day
Recommended Brands:
Pure Encapsulations NAC (N-Acetyl-L-Cysteine)
5. Omega‑3 Fatty Acids
Omega‑3s help reduce inflammation, lower triglycerides, improve insulin resistance, and may improve mood and androgen levels.
Who might benefit most:
Women with high triglycerides or inflammation markers
Those experiencing mood swings
How to choose:
Look for at least 1000 mg EPA + DHA per day
Choose molecularly distilled fish oil or algal oil (for vegans)
Confirm third‑party testing for purity
Recommended Brands:
Viva Naturals Triple-Strength Omega-3 Fish Oil
6. Magnesium
Magnesium supports blood sugar control, reduces stress & muscle tension, and can help improve sleep — all relevant for PCOS.
Who might benefit most:
Women with insulin resistance
Those with poor sleep or high stress
How to choose:
Best absorbed forms: magnesium glycinate or citrate
Start with lower doses to avoid GI upset
Recommended Brands:
View all the Best Supplements for PCOS on Thorne & receive 15% off
View all the Best Supplements for PCOS on Amazon
How to Choose the Right PCOS Supplement
With so many products on the market, it’s important to choose high‑quality, evidence‑based supplements. Here’s how:
Look for third‑party tested brands to ensure purity & potency.
Avoid proprietary blends that don’t disclose exact doses.
Pay attention to the form of nutrients (e.g., magnesium glycinate is more absorbable than magnesium oxide).
Be wary of products that promise “quick fixes” or use terms like “miracle cure.”
When in doubt, consult a dietitian or healthcare provider before starting anything new.
Start Your PCOS Wellness Journey
Managing PCOS doesn’t have to feel overwhelming — and you don’t have to do it alone.
I can help you create a personalized plan that combines nutrition, lifestyle changes, and targeted supplements so you can feel your best.
Ready to take the next step? Book a session with me or explore my PCOS‑friendly meal plans to get started.
Or — if you’d like personalized supplement recommendations tailored to your symptoms & goals, simply fill out the form below.
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DISCLAIMER
The information available from NutritionbyBre is for educational purposes only; it is not intended to diagnose, treat, or mitigate any disease. Please consult your health care professional about new dietary choices or supplements that may interact with medication.
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