GLP‐1: Managing Side Effects

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Glucagon-like peptide‐1 receptor agonists (GLP‐1 RAs) — such as semaglutide, liraglutide, and dulaglutide — are powerful tools for weight management and type 2 diabetes. They work by slowing gastric emptying, reducing appetite, and improving insulin sensitivity.

However, because of their effects on the gut and metabolism, many people experience side effects during the first few weeks or months of treatment. The most common include constipation, nausea, and fatigue.

The good news? With the right strategies, you can minimize discomfort and stay on track with your health goals. This section will explain why these symptoms occur, and provide practical, evidencebased solutions you can use immediately.

Glucagon-like peptide‐1 receptor agonists (GLP‐1 RAs) — such as semaglutide, liraglutide, and dulaglutide — are powerful tools for weight management and type 2 diabetes. They work by slowing gastric emptying, reducing appetite, and improving insulin sensitivity.

However, because of their effects on the gut and metabolism, many people experience side effects during the first few weeks or months of treatment. The most common include constipation, nausea, and fatigue.

The good news? With the right strategies, you can minimize discomfort and stay on track with your health goals. This section will explain why these symptoms occur, and provide practical, evidencebased solutions you can use immediately.